FerrDb is the world鈥檚 first manually curated database for regulators and markers of ferroptosis and ferroptosis-disease associations. It will be routinely updated to support long-term service. The data in FerrDb is free to download and use.

Ferroptosis is a new mode of regulated cell death that depends on iron. Cells die from the toxic accumulation of lipid reactive oxygen species inside. It is tightly linked to a variety of human diseases, such as cancers and degenerative diseases. The ferroptotic process is complicated and consists of a wide range of metabolites and biomolecules. Even though great progress has been achieved, the mechanism of ferroptosis remains enigmatic. We are in an era of knowledge explosion, so it is of importance to find ways to organize and utilize data efficiently. We noticed there lacks high-quality knowledgebase in ferroptosis research, so the database was created.